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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26e50486225d47bb9549409aae5838b373b676ca05d61c6c2d435b5032205c1a' 
  AND token = 'G8mzKS3f+kTE0fG7q6dXR2oPcAB/wXBcqA5jbum3Ils=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}