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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '666ce68efdd155a792ed78f1daf25e5f9a5133ba4e5e279e4fae767a4c259a79' 
  AND token = 'QuzZMv//PbqeySoqsiz0eCeKLiO4iIJJRgpO9eQ+fNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}