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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '975dbd6f1523a64a18c9e3f13d1de6e23da77019fbbbf8834ec91707ee34c611' 
  AND token = 'VTSfgsoK7JazhYrjO1YEa8UTdZgycRuM9/B1N47hxwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}