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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66bda886bd17364c61bf4f2f81affe0de807dbf066a419b87416f4e1167166fd' 
  AND token = 'lUWf8ywcWrn32ftSK+xwVm21TUh7m3VXnJX3L4zouDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}