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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cb146722e8182bec072f190b1649644118c73ec082a9f658d3dcafe25b4a77a' 
  AND token = 'mAx1rsCkaL9F86h9w+iGMAzW1rwbfYEuEFFLI7sxt4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}