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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7553720730ff42891b2141973104ffcc22309d3f1e6955e6f2a24448a52572ab' 
  AND token = 'RpQKSE3hAJ76AjEQBo9nrt05zL6kU6vsHsxrGl/tnw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}