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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '927b6e41700ae1e00c03fde4bec66c67540a4953f319ca01c9f28e4e0872e016' 
  AND token = 'RNVJwskbpMibEJiQoFftz+dUs+IsTcDgqv3wUhKg5Jw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}