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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2253403cfdcfce4f75d766d647d178365aea6bb817be5223fdb60c4165660feb' 
  AND token = 'C7C4xVks17YxaIT48SMyM0Yzuaxv5OoB2WEluEXc3sw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}