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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8918f1eca75ca1c544090a49f6257e9072e5da1dbd1ded7da63e8e9dc7e5274c' 
  AND token = 'bwDy7RgPOw98zmmqWMZdn9PKSlXAT2zVfRSXKkTd1us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}