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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7edc1422a403635bb219e49b1bf4f23dc14358eff391ce8788ae41473cf1c3a8' 
  AND token = 'QcHCJ4z3Ty/xTOYSZHscg+xHSOO9iS/6elGAT6rY93I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}