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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c594a36c1e7b91a42b8d0d805a45833bd044cdfb02ce0c21399d2c24cb25760' 
  AND token = 'e/XyngkCDFcoSUVrwuYr8IO2YU8lSaQ3h/5poAqdTdI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}