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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd65a994a0b11e5c475b9d1162feb42ab9909a01794d6cc15cc95d5d635f51d54' 
  AND token = 'Bnu21c/dDCRYBwll/WO9T28sQNZjDdYB2MFJhY/DpC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}