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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c541916a7c895f1cf5eb88ea1b01452721d01bafbe2609bd5e247c9a0a4a98c5' 
  AND token = 'jFcWlugNrS/rCD0e+J555/iYiqTxDTe2TY/Vrg0wbuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}