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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5af6b10e2231fc2b954a673f7787af4525de86abae4956784d7eec9b871d6c63' 
  AND token = 'Z9ZB45IpV/9bDZJu0/umoK1pg+AKx5beKbT5/DJt+Z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}