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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f4865267b24a510e652083df72020f5a84f3b55e9f912429a221f356b925030' 
  AND token = 'xoDf0tu32izDR2Lm7zPn03TZBPNdTMg1gwiBRPyAj44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}