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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '178a6fc9e52f7fd542fa2fe635be528091cb9090e88518ffa3dab27afca57a69' 
  AND token = 'dJomSXXqmzJX1ifZte1aSUYark90TZbPOpWhPUp6rJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}