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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '761cfeebe80b5adaead9cc2edb38818df189f8e7fa40e18c118b1c390130bf99' 
  AND token = 'bprPlpTI7gjEwEnJeZwtJrY/wXqj8YG2pJoosBfoJzg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}