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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3de7469eddb13cb91fd4343b1a9d44ddc37861278fb4ae44cabe811a2f30edaf' 
  AND token = 'MhDPuC6y2pa3o1tx1/F6HWz13rsOaGlPIpeK+iHsV5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}