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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80ce9242ee587cb55e3139f140a1fa548d06a429579f25b85f37ee7e4ef87fbd' 
  AND token = 'ssp31NRdr/OD1KhUOpQN3NFkhLfmrpyEc+37X2basB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}