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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a0a893f6eddc917fe04a66212a994afca4982a5c82ee12d34ae1a2f8629b1f0' 
  AND token = 'Vxxq8NgXkJrWU2wazOS5fxd1i047Mx5MJxPbzuYTsOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}