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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e40c3f3affb3ac23a30bb9e905765e7ac02c2690a4c27d459aa5ab259b7d6602' 
  AND token = 'HEFJnuGBh9W+eHDWoaTGbzq/FR2DNXaVfIMCKma3XCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}