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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25e73e2a3a8cbb48685537a0d98bba85e1ca2c55d69e07c5796b55f4a6a2d99c' 
  AND token = 'e+ex/nQsDpcYKYajAz67F4lCQrTd/QOa9N3Zdv4UqNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}