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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10fe266f56879dcbc215a32cd7409302884f8853e0c6e3f644e388effe3b8494' 
  AND token = 'Xlc3ZzPBEgi0POwh4J4LZ+wZNaZL0MiGeM33YmzfFJg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}