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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c227f2b6806ab17ac8aced8827c30a79968afafcf981703a342f9b7b758d57ad' 
  AND token = '8NKtUpE1atVecUTGVwMyloDtjaf8vIA2x3mRNcWynnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}