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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '581d314c8564094e8561338ffb0eecda29bcc65d70f757d48ec923a8f3e723c8' 
  AND token = 'BZjxfZzyXYt1EuQlt9+j5m3enPCTXgzESEzFE9UcCZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}