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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d773324b935c22e31483240dfe2800ee5f0294b33cb71ec59a6f76b9ec83fe2' 
  AND token = 'ZYyyeH6DA6p8dTCWHaERxWsiEL4w9JrxIe+Rp3cle1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}