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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ca9f804d0be3de4f647a6674634c9479342ece51aac3b729b193377b9f9b0ff' 
  AND token = 'PxsIxah6hW/sFttH2vPXKrs8t7vRf8GsCJb8meyqpTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}