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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '102258bb50a1661bf71adc245ca86493421d4b8a8dadb40a47d05b372094811e' 
  AND token = 'Vky3gW75d15vaLfMdAuntgzRV0mO/rDyi8GP9tEd0w4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}