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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c65984f69f2b89b4520885f839822f916a1c5d0b66c0578fe9dbbb9f9b4fc505' 
  AND token = 'wbwqzuFjQbqORQu+cdmFkT9738G0Nj6ZKmLl+X6y0lQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}