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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0d3ec565c2d373f3afef65af30b0b61312bf9fa6b7f1228491c353dfa3ca584' 
  AND token = 'I73R/NpXCBeJa3GpchaUplzwzYZ2kzI+kL/Sy/GkD8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}