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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77a0d1b546ad94ada4db0b813cd33466cc3e037ab5ab2db33be6def128d15895' 
  AND token = 'E6aU/FFlTKkjD1vqchlG91RVr6L3XNQLKz2OWQ6Qk+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}