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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b88c6f12e1c6542642841675667665a87d46080d9f8510b18ba7d8e96c51f238' 
  AND token = 'S4r/ccF+K5MiCXpOW5+Tr3CGb2+GQYwrHXXzz5n34F0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}