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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72ca1ad59ddb4f67da5f610690508a949c3db902c3dfc3e52418232b975b0a31' 
  AND token = 'b5J9nN9+msapcwaDKUZISNrDCn74Ok2KLh6UMpy+Ad4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}