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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c360718304ac969543474f654d614cf60cbe1e8e3e912bd04d68253ce4a28346' 
  AND token = 'D27ZRewJeUFLsD8m67s4U4PzPoY8zYfWtv99kd14pBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}