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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e538767df794af09e65414f550090540f729a2eafac1ad8d0677aaae4d7959a' 
  AND token = 'FiaXRIZYwRy11T8ee34Ulmf5V4NJJnBJd3e/ltGwJNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}