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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e685d2d1c78702c1ceb4645f6e523114d0f2fb70bb4d2254cae11f3a0fe6609b' 
  AND token = 'H5dKY39fe5yR3eUGUImqsMQv8jg6sxNuSH2JpJl6Yg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}