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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46f60cdff2d6d745a65182a5715348a2122192e2260d64c3006fc74c80cba413' 
  AND token = 'eZU2tZzgiYak3DsQUvxzdcECpcG0m1yznTkbnY9N6oY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}