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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b73f01f343b9ffc16386cc7b9eaf3ddd2fce3e9fa31a386538bc0b2f2d0262e' 
  AND token = 'UsrkJIND7g8SJUzQT7vBq1tQY15e8MakiORUUgdP73I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}