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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a3cfaa3453e41a696d6688087f515a10203c378c29440cd3745dbee4b578c66' 
  AND token = '6bZU7RP3QNqLbtMMagX3ddU4E8j5q3FliCXNV28OFYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}