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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70aa2859ea7f9500abee50dc010746e94b5e2a6dcea361d6e6e9abc1b937a966' 
  AND token = 'Dt6dhvqBrO+E+V/OEakQb4cyaLd/5L+03oc4LCpbWng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}