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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7fad8a263f1176b4544d1f3f543a6f56a1151ee815004eef56801c0d08ce19a' 
  AND token = 'v5S2yGcenOWAp/JGKHRTtufs7hEKkT/8fM5PY0hG4ow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}