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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2507b81cc612dc2605a1935ba9aa44c4c3673973f4c80fb9500eb9191532a1aa' 
  AND token = 'ewRVvMP4lNuEfJrwR6NsAdTe7cVv/JNg+ZEfTJT/XNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}