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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03a72f3941be0e15681f04da3a9dca42257ad566986dd557b4184455f0ea3322' 
  AND token = 'Vcoa+FsZ9bFfS5VQOLk9GbEDtssXPME7h7KHUGSFMgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}