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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db35d3767b8c4416648b4c523e3fe0bd0b3845341d03f8f7cce2be61c012744d' 
  AND token = 'B6DGX1tdcEKUDr/l5DFZx1X1hiChLpWoOalk1J5fWuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}