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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cba4797b1818a588fc7b684c8687ea3a565ab51048435f33106b0a55b35f83e' 
  AND token = 'pxu6/vAbEbqIfqCLwYuuiD0WqJwRbboCut3DQGp+VJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}