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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9fdf025a820a3e36e620142c6f41906d0489c4de2c42cf94853b8f5a51152e3' 
  AND token = 'qtQ+Lr0snU4J5HZvlJeyriQIQQmY2KKhClqHPldn6AY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}