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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ca83bd42697f78e0d33c9af3f9bb80e105e2cacea6e03b3aa6649885664306d' 
  AND token = 'LrSsD1qV1Ui23I/8/DTNWyPw2PFtNJp4UVURIPS1lP8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}