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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f3208910585b5ac5102bb3c8fc8b120dd52b4b7a59e119e587e318c3b600660' 
  AND token = 'J1Ke+m+17XUwsr37AKwItvo0AGgx3SpGnF14gA/I9FE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}