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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a5c1fe178820b77c8cb3da671aa0a1d3070cb418befeacca599f037c2b052a2' 
  AND token = '28wmJ9Geix0/iMpZT5I7/zvsWjQY78zWESE54J86V8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}