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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ad0926a03d3ec48d4c18dfa9eccc98c2cf4fe1ab96be1da25e46e517d5f4659' 
  AND token = 'Duy+JU9pZbNhQbbjpw+l3q88XTKWdcbYq9ACyk9/DxA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}